Vevo 770 High Resolution Imaging System is a high resolution echocardiograph designed for measuring cardiac function and blood dynamics in small experimental animal such as mice. Purchased in 2005, this machine enables the visualization and quantification of small animal anatomical targets, hemodynamics and therapeutic interventions with resolution as low as 30 microns. Because it is non-invasive, longitudinal monitoring and quantification of phenotypes, therapeutic regimes can be monitored in the same animal over time. This system features:
1. High Frequency RMV™ Scanheads;
· 30 micron resolution
· Frame rates up to 240 fps
· Wide selection of RMV Scanheads for a variety of applications
2. Expandable Imaging and Processing Option;
· Power Doppler for blood flow quantification & anatomical identification
· M-Mode single line acquisition allowing for high-temporal resolution of cardiovascular functional
· Anatomical M-Mode for adjustable anatomical orientation in M-Mode imaging
· 3D Imaging & Volume Analysis
· Contrast Imaging for perfusion and molecular endothelial cell surface marker analysis
· Advanced measurements & quantification
3. Open architecture data management, flexible image output options;
4. Mobile - true plug & play for any lab.
This system comes with a software package for cardiovascular research, enabling the following measurements:
1. B-mode (2D) imaging for anatomical visualization and quantification.
2. M-mode for visualization and quantification of wall motion in cardiovascular research, single line acquisition allows for the very high-temporal (1000 fps) resolution necessary for analysis of LV function.
3. Anatomical M-Mode for adjustable anatomical orientation in reconstructed M-Mode imaging.
4. Pulsed-Wave Doppler (PW) for quantification of blood flow.
5. Power Doppler for detection and quantification of blood flow in small vessels not visible in B-mode.
6. Tissue Doppler for quantification of myocardial tissue movement; for example, in assessing diastolic dysfunction and myocardial strain.